Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14772309 | 0.85 | S1PR4 (0.41) | NPC1POLBRAB9AS1PR4ALDH1A1 | |
| SCHEMBL264251 | 0.84 | KDM4E (0.53) | NPC1RAB9AS1PR4TSHRALDH1A1 | |
| SCHEMBL16094497 | 0.77 | ALDH1A1 (0.41) | RAB9AS1PR4TSHRALDH1A1HPGD | |
| SCHEMBL27361645 | 0.76 | MAPT (0.40) | TSHRALDH1A1HPGDKDM4EMAPK1 | |
| SCHEMBL17150153 | 0.75 | TRPV3 (0.38) | ALDH1A1HPGDS1PR1S1PR3KDM4E | |
| SCHEMBL18149437 | 0.74 | KMT2A (0.43) | NPC1POLBRAB9ATSHRALDH1A1 | |
| SCHEMBL2893830 | 0.72 | TTR (0.46) | POLBKDM4EHSD17B10KCNQ3KCNQ2 | |
| SCHEMBL31172660 | 0.71 | PDE4D (0.42) | POLBTSHRALDH1A1HPGDS1PR1 | |
| SCHEMBL17521665 | 0.71 | S1PR4 (0.55) | S1PR4ALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL29738152 | 0.71 | ALDH1A1 (0.45) | NPC1POLBRAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015152368-A1 | OXAZOLIDINONE AND OXAZINANONE DERIVATIVES | 大正製薬株式会社 | 2015-10-08 | — | — | WO | disclosed |