Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904775 | 0.94 | THRB (0.56) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL4059175 | 0.92 | MAPT (0.62) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL14399793 | 0.92 | MAPT (0.62) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL4063764 | 0.92 | MAPT (0.62) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL8905556 | 0.89 | MAPT (0.52) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL8904371 | 0.89 | THRB (0.65) | MAPTSMN1; SMN2THRBKMT2APLA2G1B | |
| SCHEMBL9333023 | 0.89 | MAPT (0.52) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL8903130 | 0.88 | MAPT (0.51) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL8903841 | 0.88 | MAPT (0.51) | MAPTSMN1; SMN2NPC1RAB9ACASP3 | |
| SCHEMBL9333432 | 0.88 | MAPT (0.51) | MAPTSMN1; SMN2NPC1RAB9ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150284636-A1 | LIQUID-CRYSTALLINE MEDIUM AND ELECTRO-OPTICAL LIQUID-CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-10-08 | — | — | US | disclosed |