Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.67 |
| ▸ | CCNK | O75909 | 11/20 | 0.67 |
| ▸ | CDK12 | Q9NYV4 | 11/20 | 0.67 |
| ▸ | CDK7 | P50613 | 10/20 | 0.67 |
| ▸ | CCNT1 | O60563 | 9/20 | 0.67 |
| ▸ | CDK9 | P50750 | 9/20 | 0.67 |
| ▸ | CCNH | P51946 | 9/20 | 0.67 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.67 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.67 |
| ▸ | MNAT1 | P51948 | 8/20 | 0.63 |
| ▸ | MAPK8 | P45983 | 8/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 8/20 | 0.59 |
| ▸ | JUN | P05412 | 7/20 | 0.59 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416312 | 1.00 | CDK2 (0.67) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL19054693 | 0.90 | CCNK (0.76) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL17150427 | 0.90 | CCNK (0.76) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL19024770 | 0.90 | CCNK (0.76) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL6039764 | 0.90 | CDK2 (0.78) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL29994490 | 0.90 | CDK2 (0.78) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL17150707 | 0.89 | CDK7 (0.67) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL19024524 | 0.89 | CDK7 (0.67) | CDK2CCNKCDK12CDK7CCNT1 | |
| Hydrochloric Acid SCHEMBL19024517 | 0.89 | CCNK (0.75) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL20416424 | 0.89 | CDK7 (0.67) | CDK2CCNKCDK12CDK7CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183355-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2017-06-29 | — | — | US | disclosed |
| WO-2015154039-A2 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | SYROS PHARMACEUTICALS, INC. (US) | 2015-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183355-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASE 7 (CDK7) | CDK7, CDK3, CDK9 | CDK2 7/4885CCNK 8/4885CDK12 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.