Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 14/20 | 0.78 |
| ▸ | CCNK | O75909 | 12/20 | 0.78 |
| ▸ | CDK12 | Q9NYV4 | 12/20 | 0.78 |
| ▸ | CDK7 | P50613 | 11/20 | 0.78 |
| ▸ | CCNT1 | O60563 | 10/20 | 0.78 |
| ▸ | CDK9 | P50750 | 10/20 | 0.78 |
| ▸ | CCNH | P51946 | 10/20 | 0.78 |
| ▸ | CCNE1 | P24864 | 8/20 | 0.78 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.78 |
| ▸ | MNAT1 | P51948 | 9/20 | 0.72 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.66 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.66 |
| ▸ | JUN | P05412 | 6/20 | 0.66 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6039764 | 1.00 | CDK2 (0.78) | CDK2CCNKCDK12CDK7CCNT1 | |
| Hydrochloric Acid SCHEMBL17141264 | 0.99 | CDK2 (0.76) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL29596542 | 0.94 | CCNK (0.89) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL30523927 | 0.94 | CCNK (0.89) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL17150537 | 0.94 | CCNK (0.89) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL25328316 | 0.94 | CCNK (0.89) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL17141346 | 0.90 | CDK2 (0.79) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL17150629 | 0.90 | CDK2 (0.67) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL20416312 | 0.90 | CDK2 (0.67) | CDK2CCNKCDK12CDK7CCNT1 | |
| SCHEMBL25329765 | 0.89 | CDK2 (0.83) | CDK2CCNKCDK12CDK7CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108276382-B | Cyclin-dependent kinase inhibitor and application thereof | 南京圣和药物研发有限公司 | 2022-10-18 | — | — | CN | disclosed |