Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 18/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17152371 | 0.82 | POLR1A (0.34) | — | |
| SCHEMBL17152358 | 0.82 | FGFR1 (0.32) | — | |
| SCHEMBL17152435 | 0.79 | KDM1A (0.37) | — | |
| SCHEMBL17152249 | 0.79 | KDM1A (0.37) | — | |
| SCHEMBL17152322 | 0.79 | KMT2A (0.48) | — | |
| SCHEMBL17152625 | 0.76 | HRH3 (0.33) | — | |
| SCHEMBL6053655 | 0.76 | ALDH1A1 (0.36) | — | |
| SCHEMBL17152366 | 0.75 | BTK (0.34) | — | |
| SCHEMBL15203457 | 0.75 | DPP4 (0.35) | — | |
| SCHEMBL17152479 | 0.74 | DPP4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |