Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17152435 | 1.00 | KDM1A (0.37) | KDM1AMAOAMAOBL3MBTL3BTK | |
| SCHEMBL17152371 | 0.87 | POLR1A (0.34) | BTK | |
| SCHEMBL17152479 | 0.82 | DPP4 (0.47) | — | |
| SCHEMBL17152358 | 0.82 | FGFR1 (0.32) | — | |
| SCHEMBL17152194 | 0.79 | DRD3 (0.35) | — | |
| SCHEMBL17152542 | 0.76 | L3MBTL3 (0.40) | L3MBTL3HRH3MCHR1 | |
| SCHEMBL17152254 | 0.76 | DPP4 (0.38) | — | |
| SCHEMBL17152419 | 0.75 | KDM4E (0.36) | L3MBTL3 | |
| SCHEMBL17152305 | 0.75 | AGTR2 (0.44) | MCHR1 | |
| SCHEMBL17152625 | 0.75 | HRH3 (0.33) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |