Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.50 |
| ▸ | DPP4 | P27487 | 15/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28071502 | 0.86 | DPP7 (0.47) | DPP7DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL28071509 | 0.85 | DPP7 (0.46) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL7817249 | 0.83 | DPP7 (0.51) | DPP7DPP4DPP8DPP9SLC7A5 | |
| SCHEMBL1707036 | 0.83 | DPP7 (0.51) | DPP7DPP4DPP8DPP9SLC7A5 | |
| SCHEMBL1707035 | 0.83 | DPP7 (0.51) | DPP7DPP4DPP8DPP9SLC7A5 | |
| SCHEMBL18774974 | 0.81 | MMP1 (0.51) | DPP7DPP4DPP8DPP9SLC7A5 | |
| Hydrochloric Acid SCHEMBL11172704 | 0.81 | DPP7 (0.50) | DPP7DPP4DPP8DPP9SLC7A5 | |
| SCHEMBL20413342 | 0.80 | DPP4 (0.45) | DPP7DPP4DPP8DPP9SLC7A5 | |
| SCHEMBL13995145 | 0.80 | DPP4 (0.45) | DPP7DPP4DPP8DPP9SLC7A5 | |
| Hydrochloric Acid SCHEMBL11181621 | 0.80 | DPP7 (0.50) | DPP7DPP4DPP8DPP9SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |