SCHEMBL28071502

SCHEMBL28071502

CC(S)CC(N)C(=O)N1CCSCC1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 7/20 0.47
DPP4 P27487 15/20 0.45
DPP8 Q6V1X1 4/20 0.45
DPP9 Q86TI2 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28071509 0.98 DPP7 (0.46) DPP7DPP4DPP8DPP9
SCHEMBL17152248 0.86 DPP7 (0.50) DPP7DPP4DPP8DPP9
SCHEMBL16435187 0.77 DPP7 (0.59) DPP7DPP4DPP8DPP9
SCHEMBL18722240 0.76 DPP4 (0.50) DPP7DPP4DPP8DPP9
SCHEMBL28071497 0.76 DPP4 (0.50) DPP7DPP4DPP8DPP9
SCHEMBL28071493 0.76 DPP4 (0.50) DPP7DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL27868992 0.76 DPP7 (0.50) DPP7DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL27868993 0.76 DPP7 (0.50) DPP7DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL28071551 0.74 DPP4 (0.49) DPP7DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL28071553 0.74 DPP4 (0.49) DPP7DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102453001-B Thiomorpholine compounds and its production and use INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) 2016-06-01 CN disclosed