Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 2/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17152324 | 0.86 | CACNA1B (0.53) | CACNA1BOPRD1KMT2ADPP7MEN1 | |
| SCHEMBL7040140 | 0.81 | CACNA1B (0.79) | CACNA1BOPRD1DPP7 | |
| SCHEMBL7045451 | 0.80 | CACNA1B (0.73) | CACNA1BOPRD1KMT2ADPP7 | |
| SCHEMBL785972 | 0.80 | JAK2 (0.54) | AGTR2KMT2AMEN1JAK2JAK1 | |
| SCHEMBL17152359 | 0.79 | DPP4 (0.43) | CACNA1BOPRD1KMT2ADPP7 | |
| SCHEMBL7280301 | 0.79 | LTA4H (0.63) | AGTR2KMT2AMEN1JAK2JAK1 | |
| SCHEMBL4291577 | 0.77 | CACNA1B (0.49) | CACNA1BOPRD1KMT2A | |
| SCHEMBL4286101 | 0.77 | CACNA1B (0.49) | CACNA1BOPRD1KMT2A | |
| SCHEMBL4277519 | 0.77 | CACNA1B (0.49) | CACNA1BOPRD1KMT2A | |
| SCHEMBL7040537 | 0.77 | CACNA1B (0.59) | CACNA1BOPRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |