Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | LARS1 | Q9P2J5 | 3/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8268603 | 1.00 | SLC7A5 (0.48) | SLC7A5SCN9AMMP1MMP2MMP3 | |
| SCHEMBL17152494 | 0.88 | SLC7A5 (0.52) | SLC7A5SCN9ALARS1ANPEPRNPEP | |
| SCHEMBL15958714 | 0.84 | SLC7A5 (0.48) | SLC7A5SCN9AMMP1MMP2LARS1 | |
| SCHEMBL16327076 | 0.84 | SLC7A5 (0.48) | SLC7A5SCN9AMMP1MMP2LARS1 | |
| SCHEMBL26290433 | 0.81 | SLC7A5 (0.54) | SLC7A5SCN9ALARS1ANPEPRNPEP | |
| SCHEMBL10296149 | 0.81 | SLC7A5 (0.54) | SLC7A5SCN9ALARS1ANPEPRNPEP | |
| SCHEMBL18774984 | 0.81 | SLC7A5 (0.54) | SLC7A5SCN9ALARS1ANPEPRNPEP | |
| SCHEMBL20366284 | 0.81 | SLC7A5 (0.45) | SLC7A5SCN9ALARS1ANPEPRNPEP | |
| SCHEMBL22369891 | 0.80 | MMP2 (0.42) | MMP1MMP2MMP3EPHX1PKM | |
| SCHEMBL8269796 | 0.79 | SLC7A5 (0.44) | SLC7A5SCN9ALARS1ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2897939-B1 | BENZOIMIDAZOLE-CARBOXYLIC ACID AMIDE DERIVATIVES FOR TREATING METABOLIC OR CARDIOVASCULAR DISEASES | SANOFI SA (FR) | 2017-02-01 | — | — | EP | disclosed |
| US-9156796-B2 | Benzoimidazole-carboxylic acid amide derivatives as APJ receptor modulators | SANOFI (FR) | 2015-10-13 | — | — | US | disclosed |