Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 3/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.42 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.41 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | RRM1 | P23921 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17152494 | 0.84 | SLC7A5 (0.52) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL8268603 | 0.81 | SLC7A5 (0.48) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL17152607 | 0.81 | SLC7A5 (0.48) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL31129134 | 0.81 | SLC7A5 (0.50) | SLC7A5ERAP2ERAP1LNPEPGABRR1 | |
| SCHEMBL10296149 | 0.78 | SLC7A5 (0.54) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL18774984 | 0.78 | SLC7A5 (0.54) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL30440188 | 0.77 | ALDH1A1 (0.49) | SLC7A5ERAP2ERAP1LNPEP | |
| SCHEMBL19576166 | 0.77 | ANPEP (0.43) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL14623392 | 0.77 | DPP4 (0.44) | SLC7A5SCN9AANPEPRNPEPDNPEP | |
| SCHEMBL14624739 | 0.77 | DPP4 (0.44) | SLC7A5SCN9AANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |