SCHEMBL1715299

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14367311	0.81	NPC1 (0.41)	MAPK1MAOBLMNASMN1; SMN2TDP1
	SCHEMBL1714565	0.78	SMN1; SMN2 (0.41)	MAOBLMNASMN1; SMN2TDP1MEN1
	SCHEMBL11373381	0.76	SMN1; SMN2 (0.40)	TSHRMAOBLMNASMN1; SMN2TDP1
	SCHEMBL27618647	0.76	SMN1; SMN2 (0.40)	MAOBLMNASMN1; SMN2TDP1MEN1
	SCHEMBL11359074	0.75	ADAMTS4 (0.36)	MAOBSMN1; SMN2TDP1ALPLNPC1
	SCHEMBL18180481	0.75	KEAP1 (0.42)	TSHRLMNASMN1; SMN2L3MBTL1MEN1
	SCHEMBL11360806	0.74	TDP1 (0.35)	MAOBLMNASMN1; SMN2TDP1ALPL
	SCHEMBL11364194	0.74	NPC1 (0.38)	TSHRMAOBLMNASMN1; SMN2TDP1
	SCHEMBL11376847	0.73	MAP2K7 (0.39)	LMNASMN1; SMN2ALPLMEN1KMT2A
	SCHEMBL11359078	0.73	SMN1; SMN2 (0.37)	MAOBLMNASMN1; SMN2TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.