Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13205036 | 1.00 | TLR8 (0.38) | TLR8PDK2IGF1RMCHR1ELANE | |
| SCHEMBL4546505 | 0.94 | TLR8 (0.36) | TLR8PDK2IGF1RMCHR1PDE4A | |
| SCHEMBL12595641 | 0.94 | TLR8 (0.36) | TLR8PDK2IGF1RMCHR1PDE4A | |
| SCHEMBL6825504 | 0.92 | TLR8 (0.43) | TLR8PDK2IGF1RMCHR1FFAR1 | |
| SCHEMBL18718107 | 0.90 | ALDH1A1 (0.38) | TLR8PDK2IGF1RMCHR1PDE4A | |
| SCHEMBL14461295 | 0.90 | ALDH1A1 (0.38) | TLR8PDK2IGF1RMCHR1PDE4A | |
| SCHEMBL12027393 | 0.90 | ALDH1A1 (0.38) | TLR8PDK2IGF1RMCHR1PDE4A | |
| SCHEMBL11957248 | 0.87 | TLR8 (0.33) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL14322047 | 0.87 | TLR8 (0.33) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL13810504 | 0.85 | TLR8 (0.34) | TLR8IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015149911-A1 | WHITE LIGHT EMISSION | MERCK PATENT GMBH (DE) | 2015-10-08 | — | — | WO | disclosed |