Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 7/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13205036 | 0.92 | TLR8 (0.38) | TLR8IGF1RMCHR1PDK2FFAR1 | |
| SCHEMBL17153143 | 0.92 | TLR8 (0.38) | TLR8IGF1RMCHR1PDK2FFAR1 | |
| SCHEMBL4410658 | 0.89 | TLR8 (0.36) | TLR8IGF1RMCHR1PDK2 | |
| SCHEMBL1155842 | 0.88 | TLR8 (0.36) | TLR8IGF1RMCHR1PDK2FFAR1 | |
| SCHEMBL12856495 | 0.88 | PDK2 (0.39) | TLR8IGF1RPDK2FFAR1LMNA | |
| SCHEMBL13205035 | 0.86 | TLR8 (0.34) | TLR8IGF1RMCHR1PDK2FFAR1 | |
| SCHEMBL1155844 | 0.86 | TLR8 (0.36) | TLR8IGF1RMCHR1PDK2FFAR1 | |
| SCHEMBL134317 | 0.85 | TLR8 (0.34) | TLR8IGF1RPDK2FFAR1KDM4E | |
| SCHEMBL12595641 | 0.84 | TLR8 (0.36) | TLR8IGF1RMCHR1PDK2PDE4A | |
| SCHEMBL4546505 | 0.84 | TLR8 (0.36) | TLR8IGF1RMCHR1PDK2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015149911-A1 | WHITE LIGHT EMISSION | MERCK PATENT GMBH (DE) | 2015-10-08 | — | — | WO | disclosed |
| EP-1381639-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2002077060-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |