Oxyquinoline

Oxyquinoline

SCHEMBL1715327

Cc1ccnc2c([O-])cccc12.[Al+3].[O-]c1cccc2cccnc12.[O-]c1cccc2cccnc12

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 5/20 0.61
CCR8 P51685 5/20 0.61
CCR5 P51681 4/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
PSMD14 O00487 3/20 0.50
COPS5 Q92905 3/20 0.50
HTT P42858 2/20 0.46
SLC6A2 P23975 1/20 0.46
LMNA P02545 3/20 0.44
HSP90AA1 P07900 2/20 0.42
NPC1 O15118 1/20 0.42
KDM4E B2RXH2 3/20 0.41
MAPT P10636 3/20 0.41
ALOX15 P16050 2/20 0.41
HIF1A Q16665 2/20 0.41
MMP2 P08253 2/20 0.41
TSHR P16473 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254157 0.90 PSMD14 (0.59) CCR1CCR8CCR5L3MBTL1PSMD14
SCHEMBL29428976 0.90 PSMD14 (0.59) CCR1CCR8CCR5L3MBTL1PSMD14
Oxyquinoline SCHEMBL1711518 0.89 CCR1 (0.50) CCR1CCR8CCR5L3MBTL1PSMD14
Lithium Ion SCHEMBL26097523 0.87 PSMD14 (0.59) CCR1CCR8CCR5L3MBTL1PSMD14
Tiliquinol SCHEMBL553465 0.83 HTT (0.59) CCR1CCR8CCR5L3MBTL1PSMD14
Tiliquinol SCHEMBL29444794 0.83 HTT (0.59) CCR1CCR8CCR5L3MBTL1PSMD14
Oxyquinoline SCHEMBL30010853 0.83 KDM4E (0.58) CCR1CCR8CCR5L3MBTL1PSMD14
Oxyquinoline SCHEMBL61235 0.83 KDM4E (0.58) CCR1CCR8CCR5L3MBTL1PSMD14
Oxyquinoline SCHEMBL7904185 0.81 KDM4E (0.56) CCR1CCR8CCR5L3MBTL1PSMD14
Tiliquinol SCHEMBL23928052 0.80 HTT (0.59) CCR1CCR8CCR5L3MBTL1PSMD14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1755362-B1 ORGANIC EL DEVICE TOYOTA JIDOSHOKKI KK (JP) 2011-07-20 EP disclosed
US-20070018568-A1 Organic electroluminescent device KABUSHIKI KAISHA TOYOTA JIDOSHOKKI (JP) 2007-01-25 US disclosed
EP-1560469-A1 ORGANIC ELECTROLUMINESCENT DEVICE Kabushiki Kaisha Toyota Jidoshokki (JP) 2005-08-03 EP disclosed