SCHEMBL1715419

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1715342	0.90	ALDH1A1 (0.56)	ALDH1A1HPGDIDO1MEN1KMT2A
	SCHEMBL4601571	0.83	ALDH1A1 (0.70)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL9308055	0.81	ALDH1A1 (0.81)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL4441361	0.80	ALDH1A1 (0.65)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL28028789	0.79	MEN1 (0.69)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL6260651	0.78	ALDH1A1 (0.59)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL1716129	0.78	MAPK1 (0.71)	ALDH1A1MEN1KMT2ACA1CA2
	SCHEMBL7717614	0.78	ALDH1A1 (0.55)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL18986176	0.78	ALDH1A1 (0.58)	ALDH1A1HPGDMEN1KMT2ACA1
	SCHEMBL6261913	0.77	CA1 (0.58)	ALDH1A1HPGDMEN1KMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.