SCHEMBL4601571

SCHEMBL4601571

COCCCNS(=O)(=O)Cc1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
HPGD P15428 2/20 0.70
MAPK1 P28482 1/20 0.64
KMT2A Q03164 5/20 0.53
MEN1 O00255 4/20 0.53
KDM4E B2RXH2 3/20 0.50
LMNA P02545 2/20 0.50
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
MMP1 P03956 1/20 0.49
MMP2 P08253 1/20 0.49
MMP9 P14780 1/20 0.49
MMP8 P22894 1/20 0.49
MMP13 P45452 1/20 0.49
POLB P06746 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 1/20 0.47
NPC1 O15118 1/20 0.47
NPSR1 Q6W5P4 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998286 0.90 ALDH1A1 (0.60) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL9308055 0.84 ALDH1A1 (0.81) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL1715419 0.83 ALDH1A1 (0.66) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL16509294 0.83 ALDH1A1 (0.51) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL4441361 0.83 ALDH1A1 (0.65) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL2986910 0.82 ALDH1A1 (0.50) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL6260651 0.81 ALDH1A1 (0.59) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL564037 0.81 ALDH1A1 (0.77) ALDH1A1HPGDKMT2AMEN1KDM4E
SCHEMBL9307246 0.80 ALDH1A1 (0.89) ALDH1A1HPGDMAPK1KMT2AMEN1
SCHEMBL14039537 0.80 ALDH1A1 (0.48) ALDH1A1HPGDMAPK1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200131335-A1 SURFACE ACTIVE ADJUVANT RHODIA OPERATIONS (FR) 2020-04-30 US disclosed
EP-3612604-A1 SURFACE ACTIVE ADJUVANT Rhodia Operations (FR) 2020-02-26 EP disclosed
WO-2020035124-A1 SURFACE ACTIVE ADJUVANT FOR COATINGS RHODIA OPERATIONS (FR) 2020-02-20 WO disclosed
CN-110536936-A Surface-active adjuvant RHODIA OPERATIONS 2019-12-03 CN disclosed
WO-2018193009-A1 SURFACE ACTIVE ADJUVANT RHODIA OPERATIONS (FR) 2018-10-25 WO disclosed
EP-1912645-A2 THERAPEUTIC AGENT FOR DIABETES Takeda Pharmaceutical Company Limited (JP) 2008-04-23 EP disclosed
WO-2007018314-A2 THERAPEUTIC AGENT FOR DIABETES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-02-15 WO disclosed
US-5328884-A Salicylic acid salt,and amide or sulfonamide as developer KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-07-12 US disclosed
US-5250108-A Mixture of salicylic acid salt, amide and sulfonamide compounds KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1993-10-05 US disclosed
US-4824721-A CAPSULES OF OIL SOLUBLE DYES WHICH SWELL AND RELEASE DYE UPON HEATING FUJI PHOTO FILM CO., LTD. (JP) 1989-04-25 US disclosed