Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | GABRP | O00591 | 2/20 | 0.50 |
| ▸ | GABRD | O14764 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331730 | 0.93 | CA2 (0.62) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL39103 | 0.93 | CA2 (0.62) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL27871366 | 0.91 | CA2 (0.60) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL9644299 | 0.91 | CA2 (0.60) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| Hydrochloric Acid SCHEMBL5002464 | 0.91 | CA2 (0.60) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| Bromide SCHEMBL25328791 | 0.91 | CA2 (0.60) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL1238546 | 0.91 | CA2 (0.60) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| Carbamic Acid SCHEMBL9949500 | 0.89 | CA2 (0.58) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL4799226 | 0.87 | ABCC4 (0.69) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| Propionic Acid SCHEMBL29093681 | 0.85 | ALDH1A1 (0.55) | TSHRALDH1A1TDP1CA2CAMK2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015151068-A1 | SYNTHETIC ANALOGUES OF 3-IODOTHYRONAMINE (T1AM) AND USES THEREOF | UNIVERSITA' DI PISA (IT) | 2015-10-08 | — | — | WO | disclosed |