SCHEMBL1509976

SCHEMBL1509976

O=C(CS)Nc1ccc(NC(=O)CS)cc1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.64
POLB P06746 2/20 0.64
KMT2A Q03164 2/20 0.64
MAPT P10636 1/20 0.64
L3MBTL1 Q9Y468 1/20 0.64
HDAC3 O15379 4/20 0.50
HDAC4 P56524 4/20 0.50
HDAC1 Q13547 4/20 0.50
HDAC7 Q8WUI4 4/20 0.50
HDAC2 Q92769 4/20 0.50
HDAC10 Q969S8 4/20 0.50
HDAC11 Q96DB2 4/20 0.50
HDAC8 Q9BY41 4/20 0.50
HDAC6 Q9UBN7 4/20 0.50
HDAC9 Q9UKV0 4/20 0.50
HDAC5 Q9UQL6 4/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3027410 0.91 CYP1A1 (0.60) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL20204849 0.89 MEN1 (0.55) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL5804257 0.89 GAA (0.63) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL7923572 0.89 MAPT (0.59) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL5804324 0.89 SMN1; SMN2 (0.59) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL7314984 0.89 ALDH1A1 (0.58) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL7934465 0.89 KMT2A (0.73) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL4281634 0.89 POLB (0.73) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL253778 0.88 HDAC1 (0.65) MEN1POLBKMT2AMAPTL3MBTL1
SCHEMBL7937661 0.87 MEN1 (0.53) MEN1POLBKMT2AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US claimed
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US claimed
US-7923576-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2011-04-12 US claimed
EP-1215205-B1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof SONY DEUTSCHLAND GMBH (DE) 2007-11-21 EP claimed
US-20060163564-A1 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2006-07-27 US claimed
US-20060138408-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-29 US claimed
US-20060113530-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-01 US claimed
US-7030271-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY INTERNATIONAL (EUROPE) GMBH (DE) 2006-04-18 US claimed
US-20020127756-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2002-09-12 US claimed
EP-1215205-A1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof Sony International (Europe) GmbH (DE) 2002-06-19 EP claimed
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US disclosed
US-9701629-B2 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites SONY DEUTSCHLAND GMBH (DE) 2017-07-11 US disclosed
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US disclosed
US-RE44510-E1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2013-09-24 US disclosed
US-8173842-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2012-05-08 US disclosed
US-20060113530-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2006-06-01 US disclosed
US-7030271-B2 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY INTERNATIONAL (EUROPE) GMBH (DE) 2006-04-18 US disclosed
US-20020127756-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof SONY DEUTSCHLAND GMBH (DE) 2002-09-12 US disclosed
EP-1215485-A1 Selective chemical sensors based on interlinked nanoparticle assemblies Sony International (Europe) GmbH (DE) 2002-06-19 EP disclosed
EP-1215205-A1 Tuned multifunctional linker molecules for electronic charge transport through organic-inorganic composite structures and use thereof Sony International (Europe) GmbH (DE) 2002-06-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060163564-A1 Use of dithiocarbamate esters and bis-dithiocarbamate esters in the preparation of organic-inorganic nanocomposites KCNC1, VDAC1, CALCOCO2 MEN1 2239/4885POLB 2893/4885KMT2A 4067/4885
US-20060138408-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof CORO1C, EXOC1, CLINT1 MEN1 661/4885POLB 3171/4885KMT2A 3749/4885
US-20060113530-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof CORO1C, CALCOCO2, KCNC1 MEN1 750/4885POLB 3180/4885KMT2A 3959/4885
US-20020127756-A1 Multifunctional linker molecules for tuning electronic charge transport through organic-inorganic composite structures and uses thereof CORO1C, CACNG2, KCNC1 MEN1 1105/4885POLB 2983/4885KMT2A 3376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.