⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13120228 | 0.81 | M6PR (0.32) | — | |
| SCHEMBL10258938 | 0.77 | — | — | |
| SCHEMBL20169032 | 0.73 | — | — | |
| SCHEMBL17577486 | 0.72 | PPARD (0.40) | — | |
| SCHEMBL20434935 | 0.69 | — | — | |
| SCHEMBL25520154 | 0.69 | IGF2R (0.35) | — | |
| SCHEMBL21728824 | 0.69 | CHRM5 (0.36) | — | |
| SCHEMBL12289223 | 0.69 | CHRM5 (0.35) | — | |
| SCHEMBL17170506 | 0.68 | — | — | |
| SCHEMBL13620864 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975911-B2 | Antibacterial compounds and biological applications thereof | MUTABILIS (FR) | 2018-05-22 | — | — | US | disclosed |
| US-9975911-B2 | Antibacterial compounds and biological applications thereof | MUTABILIS (FR) | 2018-05-22 | — | — | US | disclosed |
| EP-2912043-B1 | NEW ANTIBACTERIAL COMPOUNDS AND BIOLOGICAL APPLICATIONS THEREOF | MUTABILIS (FR) | 2016-11-30 | — | — | EP | disclosed |
| US-20150291636-A1 | ANTIBACTERIAL COMPOUNDS AND BIOLOGICAL APPLICATIONS THEREOF | LABORATOIRE BIODIM (FR) | 2015-10-15 | — | — | US | disclosed |
| US-20150291636-A1 | ANTIBACTERIAL COMPOUNDS AND BIOLOGICAL APPLICATIONS THEREOF | LABORATOIRE BIODIM (FR) | 2015-10-15 | — | — | US | disclosed |
| US-20150291636-A1 | ANTIBACTERIAL COMPOUNDS AND BIOLOGICAL APPLICATIONS THEREOF | LABORATOIRE BIODIM (FR) | 2015-10-15 | — | — | US | disclosed |