SCHEMBL17161508

SCHEMBL17161508

COC(=O)c1nc2cc(C(F)(F)F)ccc2n1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CFTR P13569 1/20 0.46
▸ ACACB O00763 1/20 0.45
▸ KDR P35968 1/20 0.44
▸ TEK Q02763 1/20 0.44
▸ AGPAT2 O15120 1/20 0.44
▸ MAPT P10636 3/20 0.42
▸ NPC1 O15118 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ RAB9A P51151 1/20 0.42
▸ BRAF P15056 4/20 0.41
▸ RAF1 P04049 1/20 0.41
▸ PKM P14618 1/20 0.41
▸ DYRK1A Q13627 1/20 0.40
▸ CACNA1D Q01668 1/20 0.40
▸ TP53 P04637 1/20 0.40
▸ GAA P10253 1/20 0.40
▸ CNR2 P34972 1/20 0.40
▸ USP2 O75604 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17161370 0.89 CFTR (0.46) CFTRKDRTEKMAPTLMNA
SCHEMBL2364886 0.85 PKM (0.44) ACACBAGPAT2MAPTLMNAPKM
SCHEMBL2855682 0.83 JAK2 (0.46) ACACBAGPAT2MAPTLMNAPKM
SCHEMBL17092707 0.79 MAPT (0.45) ACACBMAPTNPC1LMNARAB9A
SCHEMBL20495073 0.77 NPC1 (0.42) MAPTNPC1LMNARAB9AGAA
SCHEMBL17161375 0.77 POLB (0.53) CFTRMAPTLMNAPKMGAA
SCHEMBL22954107 0.75 CFTR (0.43) CFTRKDRTEKMAPTLMNA
SCHEMBL2711203 0.75 PKM (0.49) ACACBKDRTEKAGPAT2LMNA
SCHEMBL2596342 0.75 SMN1; SMN2 (0.53) MAPTNPC1LMNARAB9APKM
SCHEMBL29043807 0.74 HDAC1 (0.42) CFTRACACBKDRTEKAGPAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 — — US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 — — US disclosed
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150289512-A1 METHOD FOR PROMOTING PLANT GROWTH FGF1, MKI67, FGF2 CFTR 4693/4885ACACB 196/4885KDR 2261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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