Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL17162178

CN(C(=O)O)C(CCC(=O)O)C(=O)O.N

nearest known ligand 0.45

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.45
TET2 Q6N021 3/20 0.41
KDM4A O75164 2/20 0.41
KDM4C Q9H3R0 2/20 0.41
KDM2A Q9Y2K7 2/20 0.41
TET3 O43151 1/20 0.41
FOLH1 Q04609 10/20 0.40
GABRP O00591 2/20 0.40
GABRD O14764 2/20 0.40
GABRA1 P14867 2/20 0.40
GABRB1 P18505 2/20 0.40
GABRG2 P18507 2/20 0.40
GABRB3 P28472 2/20 0.40
GABRA5 P31644 2/20 0.40
GABRA3 P34903 2/20 0.40
GABRA2 P47869 2/20 0.40
GABRB2 P47870 2/20 0.40
GABRA4 P48169 2/20 0.40
GABRE P78334 2/20 0.40
GABRA6 Q16445 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL17162179 1.00 CYP1A2 (0.45) CYP1A2TET2KDM4AKDM4CKDM2A
Ammonia Solution, Strong SCHEMBL17162177 1.00 CYP1A2 (0.45) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL15921817 0.98 CYP1A2 (0.46) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL16666078 0.83 FOLH1 (0.45) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL16666108 0.82 CYP1A2 (0.43) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL22551091 0.82 CYP1A2 (0.43) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL198528 0.80 CYP1A2 (0.50) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL198527 0.80 CYP1A2 (0.50) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL14729307 0.79 SLC22A6 (0.41) CYP1A2TET2KDM4AKDM4CKDM2A
SCHEMBL19389422 0.79 CYP1A2 (0.41) CYP1A2TET2KDM4AKDM4CKDM2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9730904-B2 Prophylactic/ameliorating agent for adult diseases comprising 5-aminolevulinic acid, derivative of 5-aminolevulinic acid, or salt of 5-aminolevulinic acid or the derivative of 5-aminolevulinic acid as active ingredient SBI PHARMACEUTICALS CO., LTD. (JP) 2017-08-15 US disclosed
US-20150290159-A1 PROPHYLACTIC/AMELIORATING AGENT FOR ADULT DISEASES COMPRISING 5-AMINOLEVULINIC ACID, DERIVATIVE OF 5-AMINOLEVULINIC ACID, OR SALT OF 5-AMINOLEVULINIC ACID OR THE DERIVATIVE OF 5-AMINOLEVULINIC ACID AS ACTIVE INGREDIENT SBI PHARMACEUTICALS CO., LTD. (JP) 2015-10-15 US disclosed