Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.50 |
| ▸ | PDE4A | P27815 | 7/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Methylxanthine SCHEMBL237146 | 0.85 | ADORA2A (0.64) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| 3-Methylxanthine SCHEMBL30753411 | 0.84 | ADORA2A (0.62) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| 3-Methylxanthine SCHEMBL9317914 | 0.84 | ADORA2A (0.62) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| 3-Methylxanthine SCHEMBL4020124 | 0.84 | ADORA2A (0.62) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL18704230 | 0.77 | ADORA2A (0.77) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27054264 | 0.77 | ADORA2A (0.43) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| 3-Methylxanthine SCHEMBL2791774 | 0.76 | ADORA2A (0.58) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| 3-Methylxanthine SCHEMBL4018085 | 0.75 | ADORA2A (0.52) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| 3-Methylxanthine SCHEMBL1892894 | 0.75 | ADORA2B (0.77) | ATAD2ADORA2APDE4APDE4BPDE4C | |
| Theobromine SCHEMBL4024314 | 0.74 | MAPK1 (0.75) | ATAD2ADORA2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| WO-2017064068-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2017-04-20 | — | — | WO | disclosed |
| WO-2017060488-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2017-04-13 | — | — | WO | disclosed |
| WO-2015155306-A1 | NEW TRPA1 ANTAGONISTS | ALMIRALL, S.A. (ES) | 2015-10-15 | — | — | WO | disclosed |