Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23360227 | 0.82 | PTPN1 (0.44) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL28031536 | 0.80 | RAB9A (0.57) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL12112412 | 0.79 | RAB9A (0.66) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL4853385 | 0.79 | RAB9A (0.61) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL21121348 | 0.78 | NPC1 (0.73) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL18031149 | 0.78 | NPC1 (0.73) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL19598795 | 0.78 | RAB9A (0.86) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL9068926 | 0.78 | S1PR1 (0.42) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL9212438 | 0.76 | RAB9A (0.56) | RAB9ANPC1CASP3SENP8SENP7 | |
| SCHEMBL3358354 | 0.76 | RAB9A (0.56) | RAB9ANPC1CASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |
| EP-1884511-B1 | AROMATIC ETHER COMPOUNDS,PREPARATION AND USAGE THEREOF | SHENYANG RES INST CHEMICAL IND (CN) | 2012-01-18 | — | — | EP | disclosed |
| EP-1884511-B1 | AROMATIC ETHER COMPOUNDS,PREPARATION AND USAGE THEREOF | SHENYANG RES INST CHEMICAL IND (CN) | 2012-01-18 | — | — | EP | disclosed |
| US-7786045-B2 | Aryl ether compounds and their preparation and use thereof | SINOCHEM CORPORATION (CN) | 2010-08-31 | — | — | US | disclosed |
| US-7786045-B2 | Aryl ether compounds and their preparation and use thereof | SINOCHEM CORPORATION (CN) | 2010-08-31 | — | — | US | disclosed |
| US-7786045-B2 | Aryl ether compounds and their preparation and use thereof | SINOCHEM CORPORATION (CN) | 2010-08-31 | — | — | US | disclosed |
| US-20080275070-A1 | Aryl Ether Compounds and Their Preparation and Use Thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2008-11-06 | — | — | US | disclosed |
| US-20080275070-A1 | Aryl Ether Compounds and Their Preparation and Use Thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2008-11-06 | — | — | US | disclosed |
| US-20080275070-A1 | Aryl Ether Compounds and Their Preparation and Use Thereof | SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY (CN) | 2008-11-06 | — | — | US | disclosed |
| CN-101119972-A | Aryl ether compound and preparation and application thereof | CHINA ZHONGHUA GROUP (CN) | 2008-02-06 | — | — | CN | disclosed |
| EP-1884511-A1 | AROMATIC ETHER COMPOUNDS,PREPARATION AND USAGE THEREOF | Shenyang Research Institute of Chemical Industry (CN) | 2008-02-06 | — | — | EP | disclosed |
| EP-1884511-A1 | AROMATIC ETHER COMPOUNDS,PREPARATION AND USAGE THEREOF | Shenyang Research Institute of Chemical Industry (CN) | 2008-02-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275070-A1 | Aryl Ether Compounds and Their Preparation and Use Thereof | DDT, TYR, AHR | RAB9A 1447/4885NPC1 879/4885CASP3 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.