Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | NPC1 | O15118 | 11/20 | 0.61 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.58 |
| ▸ | RELA | Q04206 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031536 | 0.96 | RAB9A (0.57) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL28217755 | 0.82 | RAB9A (0.44) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL9068926 | 0.81 | S1PR1 (0.42) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL23360227 | 0.81 | PTPN1 (0.44) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL1716409 | 0.79 | RAB9A (0.56) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL19379939 | 0.76 | RAB9A (0.63) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| 3,5-Diphenylisoxazole SCHEMBL1421260 | 0.76 | NPC1 (1.00) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL14753038 | 0.75 | RAB9A (0.57) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL18031145 | 0.75 | NPC1 (0.79) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 | |
| SCHEMBL12959175 | 0.74 | RAB9A (0.61) | RAB9ANPC1NOTUMSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297168-B2 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2007-11-20 | — | — | US | claimed |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | PROCTER & GAMBLE COMPANY, THE | 2005-09-15 | — | — | US | claimed |
| EP-2900644-B1 | HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLIN-5-THIOAMIDES | BAYER CROPSCIENCE AG (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-2752413-B1 | QUINAZOLINE DERIVATIVE AND APPLICATION THEREOF | FUJIAN MATTER STRUCTURE (CN) | 2016-03-23 | — | — | EP | disclosed |
| US-9193718-B2 | Quinazoline derivative and application thereof | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (CN) | 2015-11-24 | — | — | US | disclosed |
| EP-2900644-A1 | HERBICIDAL AND FUNGICIDAL 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLINE-5-CARBOXAMIDES AND 5-OXY-SUBSTITUTED 3-PHENYLISOXAZOLINE-5-THIOAMIDES | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-104797564-A | Herbicidal and fungicidal 5-oxy-substituted 3-phenylisoxazoline-5-carboxamides and 5-oxy-substituted 3-phenylisoxazoline-5-thioamides | BAYER CROPSCIENCE AG | 2015-07-22 | — | — | CN | disclosed |
| US-20140221402-A1 | QUINAZOLINE DERIVATIVE AND APPLICATION THEREOF | FUJIAN INSTITUTE OF RESEARCH ON THE STRUCTURE OF MATTER, CHINESE ACADEMY OF SCIENCES (JP) | 2014-08-07 | — | — | US | disclosed |
| EP-2752413-A1 | QUINAZOLINE DERIVATIVE AND APPLICATION THEREOF | Fujian Institute Of Research On The Structure Of Matter, Chinese Academy Of Sciences (CN) | 2014-07-09 | — | — | EP | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| US-8197722-B2 | Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state | THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2012-06-12 | — | — | US | disclosed |
| WO-2005074875-A2 | KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2005-08-18 | — | — | WO | disclosed |
| US-20050164120-A1 | Photopolymerizable composition | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1493757-A1 | PHOTOPOLYMERIZABLE COMPOSITION | Kyowa Hakko Chemical Co., Ltd. (JP) | 2005-01-05 | — | — | EP | disclosed |
| US-6818262-B2 | SQUARYLIUM DYES | KYOWA YUKA CO., LTD. (JP) | 2004-11-16 | — | — | US | disclosed |
| US-20030165640-A1 | Filters for electronic display device | KYOWA YUKA CO., LTD. (JP) | 2003-09-04 | — | — | US | disclosed |
| EP-1335215-A1 | Squarylium compounds as filters for electronic display device | Kyowa Yuka Co., Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
| CN-1435700-A | Electric filter for electronic display | KYOWA YUKA KK (JP) | 2003-08-13 | — | — | CN | disclosed |
| US-5585357-A | Heteroaryloxymethyl ketones as interleukin-1βconverting enzyme inhibitors | SANOFI WINTHROP INC. (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0644198-A1 | Alpha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors | STERLING WINTHROP INC. (US) | 1995-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221402-A1 | QUINAZOLINE DERIVATIVE AND APPLICATION THEREOF | ERBB4, EGFR, ERBB2 | RAB9A 1800/4885NPC1 1176/4885NOTUM 3313/4885 |
| US-20030165640-A1 | Filters for electronic display device | DRD4, DRD2, NDUFS5 | RAB9A 1435/4885NPC1 4240/4885NOTUM 2964/4885 |
| US-20050198745-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, CKMT1A; CKMT1B, CYB5R3 | RAB9A 4235/4885NPC1 4814/4885NOTUM 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.