SCHEMBL17165348

SCHEMBL17165348

NC(=O)Cc1nc(N)c2[nH]cnc2n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GDA Q9Y2T3 2/20 0.53
▸ PDPK1 O15530 1/20 0.53
▸ KDR P35968 1/20 0.45
▸ AURKB Q96GD4 1/20 0.45
▸ MGMT P16455 2/20 0.43
▸ DPP4 P27487 1/20 0.42
▸ PI4KA P42356 2/20 0.42
▸ PI4K2B Q8TCG2 2/20 0.42
▸ PI4K2A Q9BTU6 2/20 0.42
▸ PI4KB Q9UBF8 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ DRD3 P35462 1/20 0.42
▸ XDH P47989 1/20 0.42
▸ LRRK2 Q5S007 1/20 0.42
▸ NEK2 P51955 2/20 0.42
▸ PNP P00491 1/20 0.41
▸ HTT P42858 1/20 0.41
▸ CDK2 P24941 2/20 0.39
▸ CHEK1 O14757 1/20 0.39
▸ AURKA O14965 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31239223 0.88 PDPK1 (0.53) GDAPDPK1KDRAURKBMGMT
SCHEMBL8592144 0.88 PDPK1 (0.53) GDAPDPK1KDRAURKBMGMT
SCHEMBL28873092 0.84 GDA (0.49) GDAPDPK1KDRAURKBMGMT
SCHEMBL10428052 0.83 DPP4 (0.57) GDAPDPK1KDRAURKBMGMT
SCHEMBL9176120 0.80 PDPK1 (0.59) GDAPDPK1KDRAURKBMGMT
SCHEMBL11222102 0.80 PDPK1 (0.63) GDAPDPK1KDRAURKBMGMT
SCHEMBL28144662 0.79 PDPK1 (0.46) GDAPDPK1KDRAURKBMGMT
SCHEMBL17060283 0.78 PDPK1 (0.61) GDAPDPK1KDRAURKBMGMT
SCHEMBL6267288 0.78 PDPK1 (0.56) GDAPDPK1KDRAURKBMGMT
SCHEMBL29620672 0.78 PDPK1 (0.56) GDAPDPK1KDRAURKBMGMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4372102-A2 TARGET REPORTER CONSTRUCTS AND USES THEREOF RedVault Biosciences, LP (US) 2024-05-22 — — EP disclosed
EP-3464628-B1 TARGET REPORTER CONSTRUCTS AND USES THEREOF REDVAULT BIOSCIENCES LP (US) 2024-01-31 — — EP disclosed
US-20240026436-A1 METHODS AND COMPOSITIONS FOR THE AMPLIFICATION OF MRNA BAYLOR COLLEGE OF MEDICINE (US) 2024-01-25 — — US disclosed
US-20230386603-A1 POISSON SIGNAL RECOVERY FROM MULTIPLE MEASUREMENTS WILLIAM MARSH RICE UNIVERSITY (US) 2023-11-30 — — US disclosed
US-11781178-B2 Methods and compositions for the amplification of mRNA BAYLOR COLLEGE OF MEDICINE (US) 2023-10-10 — — US disclosed
US-11299769-B2 Target reporter constructs and uses thereof REDVAULT BIOSCIENCES, LP (US) 2022-04-12 — — US disclosed
EP-3129505-B1 METHODS FOR CLONAL REPLICATION AND AMPLIFICATION OF NUCLEIC ACID MOLECULES FOR GENOMIC AND THERAPEUTIC APPLICATIONS REDVAULT BIOSCIENCES LP (US) 2021-06-30 — — EP disclosed
EP-3724331-A1 METHODS AND COMPOSITIONS FOR THE AMPLIFICATION OF MRNA Baylor College of Medicine (US) 2020-10-21 — — EP disclosed
US-20200308638-A1 METHODS AND COMPOSITIONS FOR THE AMPLIFICATION OF MRNA BAYLOR COLLEGE OF MEDICINE 2020-10-01 — — US disclosed
CN-111712572-A Methods and compositions for amplifying mRNA 贝勒医学院 2020-09-25 — — CN disclosed
WO-2019118978-A1 METHODS AND COMPOSITIONS FOR THE AMPLIFICATION OF MRNA BAYLOR COLLEGE OF MEDICINE (US) 2019-06-20 — — WO disclosed
EP-3464628-A1 TARGET REPORTER CONSTRUCTS AND USES THEREOF RedVault Biosciences LP (US) 2019-04-10 — — EP disclosed
WO-2017214127-A1 TARGET REPORTER CONSTRUCTS AND USES THEREOF REDVAULT BIOSCIENCES, LP (US) 2017-12-14 — — WO disclosed
US-20170349939-A1 TARGET REPORTER CONSTRUCTS AND USES THEREOF REDVAULT BIOSCIENCES, LP (US) 2017-12-07 — — US disclosed
US-20170067097-A1 SYSTEMS AND METHODS FOR CLONAL REPLICATION AND AMPLIFICATION OF NUCLEIC ACID MOLECULES FOR GENOMIC AND THERAPEUTIC APPLICATIONS REDVAULT BIOSCIENCES, LP (US) 2017-03-09 — — US disclosed
EP-3129505-A1 SYSTEMS AND METHODS FOR CLONAL REPLICATION AND AMPLIFICATION OF NUCLEIC ACID MOLECULES FOR GENOMIC AND THERAPEUTIC APPLICATIONS RedVault Biosciences LP (US) 2017-02-15 — — EP disclosed
WO-2015157747-A9 SYSTEMS AND METHODS FOR CLONAL REPLICATION AND AMPLIFICATION OF NUCLEIC ACID MOLECULES FOR GENOMIC AND THERAPEUTIC APPLICATIONS REDVAULT BIOSCIENCES LP (US) 2016-08-25 — — WO disclosed
WO-2015157747-A1 SYSTEMS AND METHODS FOR CLONAL REPLICATION AND AMPLIFICATION OF NUCLEIC ACID MOLECULES FOR GENOMIC AND THERAPEUTIC APPLICATIONS REDVAULT BIOSCIENCES LP (US) 2015-10-15 — — WO disclosed
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