Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.53 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MGMT | P16455 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31239223 | 1.00 | PDPK1 (0.53) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL17165348 | 0.88 | GDA (0.53) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL10361596 | 0.80 | PDPK1 (0.45) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL9176120 | 0.80 | PDPK1 (0.59) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL5091266 | 0.80 | PDPK1 (0.40) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL31239225 | 0.80 | KDR (0.41) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL11222102 | 0.80 | PDPK1 (0.63) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL8594396 | 0.79 | PDPK1 (0.39) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL17060283 | 0.78 | PDPK1 (0.61) | PDPK1GDACDK2KDRAURKB | |
| SCHEMBL31239073 | 0.78 | KDR (0.42) | CDK2KDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792283-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1997-09-03 | — | — | EP | claimed |
| WO-1996015143-A1 | SYNTHESIS OF PEPTIDE NUCLEIC ACIDS (PNAs) AND ANALOGUES VIA SUBMONOMER APPROACH | CHIRON CORPORATION (US) | 1996-05-23 | — | — | WO | claimed |
| EP-0639607-B1 | Method and apparatus for degradation and sequencing of polymers which sequentially eliminate terminal residues | PERSEPTIVE BIOSYSTEMS INC (US) | 1998-01-07 | — | — | EP | disclosed |
| EP-0816379-A2 | DNA binding oligomers | BAYER AG (DE) | 1998-01-07 | — | — | EP | disclosed |
| US-5527675-A | Method for degradation and sequencing of polymers which sequentially eliminate terminal residues | MILLIPORE CORPORATION (US) | 1996-06-18 | — | — | US | disclosed |
| EP-0639607-A2 | Method and apparatus for degradation and sequencing of polymers which sequentially eliminate terminal residues | PERSEPTIVE BIOSYSTEMS, INC. (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0586474-A1 | PEPTIDE NUCLEIC ACIDS | BUCHARDT, Ole (DK) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020702-A1 | PEPTIDE NUCLEIC ACIDS | BUCHARDT OLE (DK) | 1992-11-26 | — | — | WO | disclosed |