Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.52 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 3/20 | 0.47 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938157 | 0.86 | CDC7 (0.59) | MKNK1PDPK1NPC1RAB9AKDM4E | |
| SCHEMBL38657082 | 0.74 | PDPK1 (0.57) | MKNK1PDPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11402407 | 0.73 | GDA (0.44) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL5316773 | 0.70 | CYP1A2 (0.44) | MKNK1PDPK1TP53HSD17B10LMNA | |
| 4-Methylbenzoic Acid SCHEMBL17165604 | 0.70 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2BRD4ALDH1A1 | |
| SCHEMBL284830 | 0.69 | PDPK1 (1.00) | PDPK1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL10718858 | 0.69 | PDPK1 (0.43) | MKNK1PDPK1NPC1RAB9AKDM4E | |
| SCHEMBL2930276 | 0.67 | CDK1 (0.62) | LMNABRAFPIN1TSHR | |
| SCHEMBL3388864 | 0.66 | PDPK1 (0.68) | PDPK1KDM4ESMN1; SMN2TP53HSD17B10 | |
| SCHEMBL6680758 | 0.66 | PDPK1 (0.57) | PDPK1TP53HSD17B10LMNACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151665-A1 | METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK | Laboratory Corporation of America Holdings (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015157601-A1 | METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK | SYNAPDX CORPORATION (US) | 2015-10-15 | — | — | WO | disclosed |