SCHEMBL284830

SCHEMBL284830

COc1ncnc2nc[nH]c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 1.00
CDC7 O00311 4/20 0.54
DBF4 Q9UBU7 4/20 0.54
LMNA P02545 5/20 0.52
LRRK2 Q5S007 2/20 0.52
PI4KA P42356 2/20 0.52
PI4K2B Q8TCG2 2/20 0.52
PI4K2A Q9BTU6 2/20 0.52
PI4KB Q9UBF8 2/20 0.52
DRD3 P35462 1/20 0.52
XDH P47989 1/20 0.52
CDK2 P24941 2/20 0.52
HSD17B10 Q99714 2/20 0.52
CHEK1 O14757 1/20 0.52
AURKA O14965 1/20 0.52
CHEK2 O96017 1/20 0.52
HSP90AA1 P07900 1/20 0.52
HSP90AB1 P08238 1/20 0.52
PRKACA P17612 1/20 0.52
CCNE1 P24864 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6474310 0.98 PDPK1 (0.96) PDPK1CDC7DBF4LMNALRRK2
SCHEMBL3388864 0.81 PDPK1 (0.68) PDPK1CDC7DBF4LMNALRRK2
SCHEMBL2940697 0.80 PDPK1 (0.67) PDPK1CDC7DBF4LMNALRRK2
6-[(Isopropyl)Oxy]Purine SCHEMBL8939257 0.79 PDPK1 (0.66) PDPK1CDC7DBF4LMNALRRK2
SCHEMBL9094494 0.78 PDPK1 (0.64) PDPK1CDC7DBF4LMNALRRK2
SCHEMBL2938609 0.77 PDPK1 (0.62) PDPK1CDC7DBF4LMNALRRK2
SCHEMBL9197744 0.77 PDPK1 (0.62) PDPK1CDC7DBF4LMNACDK2
SCHEMBL7027159 0.74 CDK1 (0.63) PDPK1CDC7DBF4LMNACDK2
SCHEMBL8937061 0.74 CDK1 (0.63) PDPK1CDC7DBF4LMNACDK2
SCHEMBL10338837 0.74 CDK2 (0.63) PDPK1CDC7DBF4LMNALRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560315-A2 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2025-05-28 EP claimed
CN-118782152-B Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2025-05-20 CN claimed
EP-3980554-B1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES HOFFMANN LA ROCHE (CH) 2025-03-26 EP claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
CN-118782152-A Organic heterocyclic biomarker for wild and cultivated four-large family fish population and application thereof 中国水产科学研究院长江水产研究所 2024-10-15 CN claimed
CN-113582245-B Preparation method of porous quaternary precursor inside 南通金通储能动力新材料有限公司 2023-11-14 CN claimed
CN-113735190-B Small-particle ternary precursor and preparation method thereof 南通金通储能动力新材料有限公司 2023-07-14 CN claimed
EP-3131914-B1 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV IDENIX PHARMACEUTICALS LLC (US) 2023-05-10 EP claimed
CN-115968815-A Induction method for efficiently producing full-male nibea albiflora triploid 浙江省海洋水产研究所 2023-04-18 CN claimed
US-20220333079-A1 GENETICALLY MODIFIED NK CELL LINE TRANSDUCED WITH GENE ENCODING NOVEL CHIMERIC ANTIGEN RECEPTOR AND USE THEREOF SLBiGen, Inc. (KR) 2022-10-20 US claimed
EP-0797676-A2 RECOMBINANT ADENOVIRAL VECTOR AND METHODS OF USE CANJI, Inc. (US) 1997-10-01 EP claimed
US-5659348-A APPLYING TO A SUBSTRATE XEROX CORPORATION (US) 1997-08-19 US claimed
EP-0673783-A2 Recording sheets containing purine, pyrimidine, benzimidazole, imidazolidine, urazole, pyrazole, triazole, benzotriazole, tetrazole, and pyrazine compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
EP-0540686-B1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1995-08-30 EP claimed
EP-0365556-B1 NUCLEOSIDE ANALOGUES GENENTECH INC (US) 1995-07-12 EP claimed
WO-1995011984-A2 RECOMBINANT ADENOVIRAL VECTOR AND METHODS OF USE CANJI, INC. (US) 1995-05-04 WO claimed
EP-0540686-A4 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES US COMMERCE (US) 1993-05-26 EP claimed
EP-0540686-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES. US COMMERCE (US) 1993-05-12 EP claimed
US-5118800-A Oligonucleotides possessing a primary amino group in the terminal nucleotide CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1992-06-02 US claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed