Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 7/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 3/20 | 0.47 |
| ▸ | IARS1 | P41252 | 1/20 | 0.46 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17165637 | 1.00 | P2RY6 (0.47) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL22387094 | 0.92 | P2RY6 (0.51) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL22387174 | 0.92 | P2RY6 (0.51) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL23762553 | 0.92 | P2RY6 (0.51) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| Isoleucine SCHEMBL17165641 | 0.86 | LMNA (0.53) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| Isoleucine SCHEMBL17165634 | 0.86 | LMNA (0.53) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL9601020 | 0.85 | P2RY6 (0.55) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL22387092 | 0.84 | P2RY6 (0.52) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL21345106 | 0.84 | P2RY6 (0.52) | P2RY6P2RY14NT5EP2RY2P2RY4 | |
| SCHEMBL23762552 | 0.84 | P2RY6 (0.52) | P2RY6P2RY14NT5EP2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151665-A1 | METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK | Laboratory Corporation of America Holdings (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015157601-A1 | METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK | SYNAPDX CORPORATION (US) | 2015-10-15 | — | — | WO | disclosed |