Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MTOR | P42345 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL17165634 | 1.00 | LMNA (0.53) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20459954 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL6397305 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14946394 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL453447 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL453448 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL14929347 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20967857 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20628772 | 0.87 | LMNA (0.65) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL17165639 | 0.86 | P2RY6 (0.47) | P2RY6P2RY14NT5EP2RY2P2RY4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3151665-A1 | METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK | Laboratory Corporation of America Holdings (US) | 2017-04-12 | — | — | EP | disclosed |
| WO-2015157601-A1 | METHODS AND SYSTEMS FOR DETERMINING AUTISM SPECTRUM DISORDER RISK | SYNAPDX CORPORATION (US) | 2015-10-15 | — | — | WO | disclosed |