Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17166274 | 0.93 | RAB9A (0.76) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL9806710 | 0.86 | RAB9A (0.65) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL17166043 | 0.83 | POLB (0.65) | RAB9AMEN1KMT2APOLBCA12 | |
| SCHEMBL13883813 | 0.82 | MEN1 (0.60) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL1306810 | 0.81 | RAB9A (0.76) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL13227992 | 0.81 | POLB (0.66) | RAB9AMEN1KMT2APOLBRXFP1 | |
| SCHEMBL17166311 | 0.80 | POLB (0.70) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL15614028 | 0.77 | POLB (0.69) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL14338938 | 0.77 | RAB9A (0.73) | RAB9AENPP2MEN1KMT2APOLB | |
| SCHEMBL11669212 | 0.77 | KCNK3 (0.81) | RAB9AMEN1KMT2APOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155792-B2 | RecA inhibitors with antibiotic activity, compositions and methods of use | TRUSTEES OF BOSTON UNIVERSITY (US) | 2015-10-13 | — | — | US | disclosed |