Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815924 | 0.81 | ALDH1A1 (0.42) | KDM4EGRNSORT1MAPTPLAT | |
| SCHEMBL22290279 | 0.81 | CA12 (0.45) | KDM4EGRNSORT1MAPTMEN1 | |
| SCHEMBL17796531 | 0.80 | KDM4E (0.40) | KDM4EGRNSORT1MAPTPLAT | |
| SCHEMBL26036174 | 0.79 | MEN1 (0.38) | KDM4EGRNSORT1MAPTMEN1 | |
| SCHEMBL26036175 | 0.79 | KDM4E (0.35) | KDM4EGRNSORT1MAPTMEN1 | |
| SCHEMBL30481759 | 0.78 | JMJD6 (0.37) | KDM4EMAPTGABRG2GABRB3GABRA5 | |
| SCHEMBL27163039 | 0.78 | MEN1 (0.39) | KDM4EGRNSORT1MAPTPLAT | |
| SCHEMBL27166400 | 0.78 | GRN (0.41) | KDM4EGRNSORT1MAPTPLAT | |
| SCHEMBL25216124 | 0.77 | POLB (0.45) | MEN1KMT2ARXFP1CYP2C9CYP2C19 | |
| SCHEMBL20269905 | 0.77 | LMNA (0.50) | KDM4EMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156858-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |