Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | TAS2R8 | Q9NYW2 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15163843 | 0.82 | MAPT (0.61) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| SCHEMBL15520765 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| SCHEMBL4423914 | 0.79 | MAPT (0.57) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL2722945 | 0.78 | MAPT (0.56) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| SCHEMBL17166119 | 0.78 | POLB (0.45) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| SCHEMBL22619696 | 0.72 | ALDH1A1 (0.66) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| SCHEMBL19252939 | 0.72 | MAPT (0.68) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL22619646 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL28522525 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MAPTPKML3MBTL1LMNA | |
| SCHEMBL28801119 | 0.70 | ALDH1A1 (0.51) | ALDH1A1MAPTPKML3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156791-B2 | Pyrazole compounds acting against allergic, immune and inflammatory conditions | GLAXO GROUP LIMITED (GB) | 2015-10-13 | — | — | US | disclosed |