Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.39 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2342290 | 0.88 | KMT2A (0.45) | KMT2AL3MBTL1ALDH1A1LMNANPFFR1 | |
| SCHEMBL203039 | 0.85 | MEN1 (0.46) | KMT2AS1PR5ALDH1A1S1PR1FUCA1 | |
| SCHEMBL2706345 | 0.85 | MEN1 (0.46) | KMT2AS1PR5ALDH1A1S1PR1FUCA1 | |
| SCHEMBL23464746 | 0.85 | MEN1 (0.46) | KMT2AS1PR5ALDH1A1S1PR1FUCA1 | |
| SCHEMBL23415558 | 0.81 | S1PR5 (0.53) | L3MBTL1S1PR5ALDH1A1S1PR1FUCA1 | |
| SCHEMBL17166396 | 0.81 | S1PR5 (0.53) | L3MBTL1S1PR5ALDH1A1S1PR1FUCA1 | |
| SCHEMBL25173575 | 0.80 | S1PR5 (0.56) | KMT2AL3MBTL1S1PR5ALDH1A1LMNA | |
| SCHEMBL11197364 | 0.77 | MMP13 (0.53) | KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL28943257 | 0.75 | SCN4A (0.55) | KMT2AL3MBTL1S1PR5ALDH1A1 | |
| SCHEMBL17166394 | 0.75 | KMT2A (0.41) | KMT2AL3MBTL1ALDH1A1MAPTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156858-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |