Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1947707 | 0.76 | MAPT (0.50) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL22039863 | 0.76 | MAPT (0.50) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL20146480 | 0.76 | MAPT (0.50) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL22039864 | 0.76 | MAPT (0.50) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL17986811 | 0.76 | MAPT (0.50) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL30636976 | 0.76 | MAPT (0.50) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL11197364 | 0.75 | MMP13 (0.53) | KMT2AL3MBTL1ALDH1A1TSHRMAPK1 | |
| SCHEMBL17166392 | 0.75 | KMT2A (0.42) | KMT2AL3MBTL1MAPTALDH1A1JAK2 | |
| Hydrochloric Acid SCHEMBL28654829 | 0.74 | MAPT (0.49) | KMT2AL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL2342290 | 0.73 | KMT2A (0.45) | KMT2AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9156858-B2 | Boronic acid derivatives and therapeutic uses thereof | REMPEX PHARMACEUTICALS, INC. (US) | 2015-10-13 | — | — | US | disclosed |