Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | LAP3 | P28838 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16441206 | 1.00 | CA12 (0.44) | CA12CA2CA9CA1CA4 | |
| SCHEMBL2742844 | 0.90 | CA12 (0.45) | CA12CA2CA9CA1CA4 | |
| SCHEMBL231156 | 0.90 | CA12 (0.45) | CA12CA2CA9CA1CA4 | |
| SCHEMBL18025354 | 0.89 | CA12 (0.44) | CA12CA2CA9CA1CA4 | |
| SCHEMBL10001634 | 0.87 | LTA4H (0.47) | CA12CA2CA9CA1CA4 | |
| SCHEMBL20215813 | 0.87 | LTA4H (0.47) | CA12CA2CA9CA1CA4 | |
| SCHEMBL10001633 | 0.87 | CA12 (0.47) | CA12CA2CA9CA1CA4 | |
| Hydrochloric Acid SCHEMBL5755082 | 0.86 | LTA4H (0.46) | CA12CA2CA9CA1CA4 | |
| SCHEMBL2802898 | 0.85 | CA12 (0.46) | CA12CA2CA9CA1CA4 | |
| SCHEMBL4865204 | 0.85 | CA12 (0.46) | CA12CA2CA9CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2930182-A1 | MODIFIED INSULIN POLYPEPTIDES AND THEIR USES | Ambrx, Inc. (US) | 2015-10-14 | — | — | EP | disclosed |