SCHEMBL1716672

SCHEMBL1716672

CC(C)CCCC(=O)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4C Q9H3R0 2/20 0.46
PHF8 Q9UPP1 2/20 0.46
KDM2A Q9Y2K7 2/20 0.46
KDM4A O75164 1/20 0.46
BLM P54132 1/20 0.42
KDM1A O60341 1/20 0.41
CA1 P00915 2/20 0.39
GABRP O00591 2/20 0.38
GABRD O14764 2/20 0.38
GABRA1 P14867 2/20 0.38
GABRB1 P18505 2/20 0.38
GABRG2 P18507 2/20 0.38
GABRB3 P28472 2/20 0.38
GABRA5 P31644 2/20 0.38
GABRA3 P34903 2/20 0.38
GABRA2 P47869 2/20 0.38
GABRB2 P47870 2/20 0.38
GABRA4 P48169 2/20 0.38
GABRE P78334 2/20 0.38
GABRA6 Q16445 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2213202 0.86 CA1 (0.48) KDM4CPHF8KDM2AKDM4ABLM
SCHEMBL5613242 0.83 CA1 (0.48) KDM4CPHF8KDM2AKDM4ABLM
SCHEMBL8834162 0.82 PHF8 (0.48) KDM4CPHF8KDM2AKDM4ABLM
SCHEMBL27702243 0.82 ACE (0.50) KDM4CPHF8KDM2AKDM4ABLM
SCHEMBL125280 0.80
SCHEMBL29660871 0.80 LMNA (0.53) KDM4CPHF8KDM2AKDM4ABLM
SCHEMBL1134685 0.80 KMT2A (0.59) KDM4CPHF8KDM2AKDM4AGSTK1
SCHEMBL10290202 0.78 CA1 (0.37) KDM4CPHF8KDM2AKDM4ABLM
SCHEMBL28319651 0.78 PHF8 (0.50) KDM4CPHF8KDM2AKDM4AKDM1A
SCHEMBL2527461 0.78 CA1 (0.44) KDM4CPHF8KDM2AKDM4ABLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110511127-B Method for preparing alpha-hydroxy ketone by using ethynylation reaction by-product 万华化学集团股份有限公司 2022-08-05 CN claimed
EP-1716159-B1 BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS MOMENTIVE PERFORMANCE MAT INC (US) 2011-07-13 EP claimed
EP-1697386-B1 ACTIVE INGREDIENT-RELEASING CYCLIC SILOXANES GEN ELECTRIC (US) 2007-10-10 EP claimed
CN-110511127-B Method for preparing alpha-hydroxy ketone by using ethynylation reaction by-product 万华化学集团股份有限公司 2022-08-05 CN disclosed
EP-2145042-B2 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2021-10-06 EP disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-2145042-B1 TEXTILE SCENTING HENKEL AG & CO KGAA (DE) 2018-01-17 EP disclosed
EP-2145042-A1 TEXTILE SCENTING Henkel AG & Co. KGaA (DE) 2010-01-20 EP disclosed
WO-2008135306-A1 TEXTILE SCENTING HENKEL AG & CO. KGAA (DE) 2008-11-13 WO disclosed
EP-1928992-A1 CONSUMER PRODUCTS HAVING VARYING ODORS Henkel AG & Co. KGaA (DE) 2008-06-11 EP disclosed
EP-1922398-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-05-21 EP disclosed
WO-2007028479-A1 CONSUMER PRODUCTS HAVING VARYING ODORS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed
WO-2007028477-A1 CONSUMER PRODUCTS HAVING VARYING ODOR PATTERNS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-03-15 WO disclosed