Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5613242 | 0.89 | CA1 (0.48) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL2527424 | 0.86 | — | — | |
| SCHEMBL2533371 | 0.85 | CA1 (0.41) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL2531343 | 0.85 | CA1 (0.41) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL110410 | 0.84 | CA1 (0.50) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL2531310 | 0.83 | GPR84 (0.41) | CA1BLMPTPN1KDM1AKDM4C | |
| SCHEMBL2527457 | 0.82 | CA1 (0.42) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL106845 | 0.82 | CA1 (0.42) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL128911 | 0.82 | TDP1 (0.43) | CA1BLMPTPN1KDM1ALMNA | |
| SCHEMBL2523653 | 0.81 | GPR84 (0.44) | CA1BLMPTPN1KDM1AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |