SCHEMBL17167166

SCHEMBL17167166

O=C(O)CCCCCCCNC(=O)COCCOCCOCC(=O)NCCCCCCCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PRMT1 Q99873 1/20 0.55
▸ ADRA1A P35348 1/20 0.52
▸ ITGB3 P05106 1/20 0.48
▸ ITGA2B P08514 1/20 0.48
▸ GLP1R P43220 8/20 0.46
▸ EPHX2 P34913 4/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ PLA2G2A P14555 1/20 0.44
▸ LMNA P02545 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ PMP22 Q01453 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27260850 0.92 PRMT1 (0.47) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL19645170 0.92 ADRA1A (0.53) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL26905191 0.92 GLP1R (0.53) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL27288091 0.92 GLP1R (0.50) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL22648076 0.92 GLP1R (0.53) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL27328538 0.91 ADRA1A (0.47) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL26297889 0.91 GLP1R (0.57) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL27661517 0.90 PRMT1 (0.52) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL27331406 0.90 PRMT1 (0.52) PRMT1ADRA1AITGB3ITGA2BGLP1R
SCHEMBL26904870 0.89 PRMT1 (0.45) PRMT1ADRA1AITGB3ITGA2BGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186603-B2 Heparan sulfate glycomimetic compounds and their pharmaceutical and cosmeceutical uses VICTORIA LINK LIMITED (NZ) 2021-11-30 — — US disclosed
US-20200131217-A1 HEPARAN SULFATE GLYCOMIMETIC COMPOUNDS AND THEIR PHARMACEUTICAL AND COSMECEUTICAL USES VICTORIA LINK LIMITED (NZ) 2020-04-30 — — US disclosed
US-9879041-B2 Saccharide dendritic cluster compounds as inhibitors of BACE-1 VICTORIA LINK LIMITED (NZ) 2018-01-30 — — US disclosed
US-9828341-B2 Dendritic core compounds VICTORIA LINK LIMITED (NZ) 2017-11-28 — — US disclosed
US-9828341-B2 Dendritic core compounds VICTORIA LINK LIMITED (NZ) 2017-11-28 — — US disclosed
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 UNIVERSITY OF LIVERPOOL (GB) 2017-06-01 — — US disclosed
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 UNIVERSITY OF LIVERPOOL (GB) 2017-06-01 — — US disclosed
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 — — US disclosed
US-20150291522-A1 DENDRITIC CORE COMPOUNDS CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) 2015-10-15 — — US disclosed
US-20150291522-A1 DENDRITIC CORE COMPOUNDS CALLAGHAN INNOVATION RESEARCH LIMITED (NZ) 2015-10-15 — — US disclosed
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291522-A1 DENDRITIC CORE COMPOUNDS FLOT1, DBN1, DCTN3 PRMT1 3059/4885ADRA1A 1623/4885ITGB3 266/4885
US-20200131217-A1 HEPARAN SULFATE GLYCOMIMETIC COMPOUNDS AND THEIR PHARMACEUTICAL AND COSMECEUTICAL USES GBA1, UGCG, GBA2 PRMT1 4812/4885ADRA1A 4413/4885ITGB3 2872/4885
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP PRMT1 2836/4885ADRA1A 2443/4885ITGB3 1365/4885
US-20170152279-A9 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP PRMT1 2836/4885ADRA1A 2443/4885ITGB3 1365/4885
US-11186603-B2 Heparan sulfate glycomimetic compounds and their pharmaceutical and cosmeceutical uses GBA1, UGCG, GBA2 PRMT1 4812/4885ADRA1A 4413/4885ITGB3 2872/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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