Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 7/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716766 | 1.00 | FFAR1 (0.40) | FFAR1BRD4PTGDR2ACHEBACE1 | |
| SCHEMBL1263798 | 0.93 | FFAR1 (0.40) | FFAR1BRD4KCNH2SCN3A | |
| SCHEMBL1263792 | 0.93 | FFAR1 (0.40) | FFAR1BRD4KCNH2SCN3A | |
| SCHEMBL1263790 | 0.93 | FFAR1 (0.40) | FFAR1BRD4KCNH2SCN3A | |
| SCHEMBL1716768 | 0.92 | FFAR1 (0.40) | FFAR1BRD4PTGDR2ACHEBACE1 | |
| SCHEMBL1263796 | 0.87 | FFAR1 (0.41) | FFAR1BRD4KCNH2SCN3A | |
| SCHEMBL1715708 | 0.84 | ACHE (0.39) | FFAR1BRD4PTGDR2ACHEBACE1 | |
| SCHEMBL1715706 | 0.84 | BRD4 (0.39) | FFAR1BRD4PTGDR2ACHEBACE1 | |
| SCHEMBL10087898 | 0.83 | GAA (0.38) | ACHEBACE1 | |
| SCHEMBL1263382 | 0.78 | FFAR1 (0.40) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1784173-B1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2012-01-18 | — | — | EP | claimed |
| JP-4733698-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| EP-1784173-A4 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RES INST CHEM TECH (KR) | 2009-07-01 | — | — | EP | claimed |
| EP-1784173-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | Korea Research Institute of Chemical Technology (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2005123054-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING METABOLIC BONE DISEASES CONTAINING ALPHA-ARYLMETHOXYACRYLATE DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-12-29 | — | — | WO | claimed |