SCHEMBL17167857

SCHEMBL17167857

CCCCCCCOC1OC(C(=O)O)C(OC2OC(COS(=O)(=O)O)C(OC3OC(C(=O)O)C(OC4OC(COS(=O)(=O)O)C(O)C(O)C4C)C(O)C3OS(=O)(=O)O)C(O)C2C)C(O)C1OS(=O)(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ F10 P00742 1/20 0.53
▸ BDNF P23560 3/20 0.50
▸ PTN P21246 2/20 0.50
▸ MDK P21741 2/20 0.50
▸ VEGFA P15692 5/20 0.49
▸ CXCL12 P48061 3/20 0.49
▸ BMP2 P12643 2/20 0.49
▸ SHH Q15465 2/20 0.49
▸ CCL2 P13500 2/20 0.49
▸ CXCL10 P02778 1/20 0.49
▸ CXCL8 P10145 1/20 0.49
▸ CCL5 P13501 1/20 0.49
▸ HPSE Q9Y251 9/20 0.47
▸ FGF1 P05230 6/20 0.47
▸ FGF2 P09038 6/20 0.47
▸ IFNG P01579 1/20 0.46
▸ PF4 P02776 1/20 0.46
▸ SELP P16109 1/20 0.46
▸ BMP6 P22004 1/20 0.46
▸ CCL11 P51671 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17167539 0.97 BDNF (0.51) F10BDNFPTNMDKVEGFA
SCHEMBL17167541 0.91 BDNF (0.54) F10BDNFPTNMDKVEGFA
SCHEMBL17167553 0.89 BDNF (0.55) F10BDNFPTNMDKVEGFA
SCHEMBL18914962 0.83 F10 (0.48) F10BDNFPTNMDKVEGFA
SCHEMBL17167262 0.83 HPSE (0.47) F10BDNFPTNMDKVEGFA
SCHEMBL17167546 0.82 F10 (0.45) F10BDNFPTNMDKVEGFA
SCHEMBL30013150 0.82 CXCL12 (0.56) F10BDNFPTNMDKVEGFA
SCHEMBL18914964 0.82 MDK (0.47) F10BDNFPTNMDKVEGFA
SCHEMBL14817756 0.82 F10 (0.69) F10BDNFPTNMDKCXCL12
SCHEMBL17167549 0.82 F10 (0.44) F10BDNFPTNMDKVEGFA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 VICTORIA LINK LTD (NZ) 2015-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150291644-A1 Saccharide Dendritic Cluster Compounds as Inhibitors of Bace-1 BACE1, BACE2, APP F10 3347/4885BDNF 121/4885PTN 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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