Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372416 | 0.97 | HSPD1 (0.54) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL27210077 | 0.93 | HSPD1 (0.57) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL690092 | 0.91 | HSPD1 (0.58) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL690093 | 0.88 | HSPD1 (0.44) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL17995591 | 0.86 | HSPD1 (0.57) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL9516097 | 0.85 | HSPD1 (0.45) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL17995592 | 0.83 | HSPD1 (0.46) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL13269536 | 0.83 | MEN1 (0.44) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL9770238 | 0.82 | HSPD1 (0.47) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL27576497 | 0.82 | HSPD1 (0.47) | HSPD1BLMHSPE1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716159-B1 | BICYCLIC SILOXANE COMPOSITIONS FOR THE RELEASE OF ACTIVE INGREDIENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2011-07-13 | — | — | EP | claimed |