Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPD1 | P10809 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11372416 | 0.89 | HSPD1 (0.54) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL1716951 | 0.85 | HSPD1 (0.54) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL6240550 | 0.84 | FFAR4 (0.50) | HSPD1BLMHSPE1MEN1KMT2A | |
| SCHEMBL9331686 | 0.81 | GPR84 (0.44) | HSPD1BLMHSPE1GPR84FFAR1 | |
| SCHEMBL15412278 | 0.81 | GPR84 (0.44) | HSPD1BLMHSPE1GPR84FFAR1 | |
| SCHEMBL2904335 | 0.80 | FDPS (0.46) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL7766545 | 0.80 | ACE2 (0.43) | HSPD1BLMHSPE1GPR84FFAR1 | |
| SCHEMBL690092 | 0.80 | HSPD1 (0.58) | HSPD1BLMHSPE1MEN1HPGD | |
| SCHEMBL6237470 | 0.79 | FFAR4 (0.46) | HSPD1BLMHSPE1MEN1KMT2A | |
| SCHEMBL27210077 | 0.78 | HSPD1 (0.57) | HSPD1BLMHSPE1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0372527-B1 | TOPICAL COMPOSITIONS CONTAINING DICLOFENAC | ALTERGON S.A. (CH) | 1993-05-12 | — | — | EP | disclosed |
| EP-0372527-A1 | Topical compositions containing diclofenac | ALTERGON S.A. (CH) | 1990-06-13 | — | — | EP | disclosed |