Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.68 |
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21091041 | 0.86 | CASR (0.53) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL3511611 | 0.85 | TSHR (0.57) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL13255390 | 0.83 | LMNA (0.51) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL15670749 | 0.81 | GAA (0.51) | KDM4EPOLBATMMAPTKMT2A | |
| 2-Methylaminobenzoic Acid Methyl Ester SCHEMBL29364831 | 0.81 | KDM4E (1.00) | KDM4EPOLBATMMAPTKMT2A | |
| 2-Methylaminobenzoic Acid Methyl Ester SCHEMBL165559 | 0.81 | KDM4E (1.00) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL13255409 | 0.80 | LMNA (0.52) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL2424998 | 0.80 | KDM4E (0.70) | KDM4EPOLBATMMAPTKMT2A | |
| SCHEMBL8210808 | 0.80 | KDM4E (0.70) | KDM4EPOLBATMMAPTKMT2A | |
| 2-Methylaminobenzoic Acid Methyl Ester SCHEMBL29271837 | 0.79 | KDM4E (0.96) | KDM4EPOLBATMMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2914577-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-13 | — | — | EP | disclosed |
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-26 | — | — | US | disclosed |
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-10-26 | — | — | US | disclosed |
| US-9718762-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-9718762-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-08-01 | — | — | US | disclosed |
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-15 | — | — | US | disclosed |
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150291510-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | KDM4E 2627/4885POLB 4599/4885ATM 2318/4885 |
| US-20170305839-A1 | INSECTICIDAL COMPOUNDS | ACHE, HDAC6, TUBA3C | KDM4E 2440/4885POLB 4549/4885ATM 2245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.