Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17885936 | 0.99 | P2RY6 (0.62) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL24179730 | 0.87 | P2RY6 (0.65) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19057217 | 0.87 | P2RY6 (0.65) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL17175241 | 0.86 | P2RY6 (0.58) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19732526 | 0.85 | P2RY6 (0.67) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL17885893 | 0.85 | P2RY6 (0.60) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19057216 | 0.85 | P2RY6 (0.62) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL20953611 | 0.84 | P2RY6 (0.65) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19732544 | 0.84 | P2RY6 (0.69) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL19732505 | 0.83 | P2RY6 (0.64) | P2RY6LMNAALDH1A1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2024-02-29 | — | — | US | disclosed |
| WO-2023150540-A1 | HYDROXAMIC ACID MACROCYCLIC AGENTS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| US-11691997-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| EP-3129350-B1 | MACROCYCLES | LUMIPHORE INC (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20210290787-A1 | MACROCYCLE CONJUGATES | LUMIPHORE, INC. | 2021-09-23 | — | — | US | disclosed |
| US-20200405887-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2020-12-31 | — | — | US | disclosed |
| US-20200062757-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2020-02-27 | — | — | US | disclosed |
| WO-2019173639-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| US-10273256-B2 | Macrocycles | LUMIPHORE, INC. (US) | 2019-04-30 | — | — | US | disclosed |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | LUMIPHORE, INC. (US) | 2019-03-26 | — | — | US | disclosed |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. | 2018-07-12 | — | — | US | disclosed |
| WO-2018045385-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | LUMIPHORE, INC. (US) | 2018-03-08 | — | — | WO | disclosed |
| US-20170183365-A1 | MACROCYCLES | LUMIPHORE, INC. | 2017-06-29 | — | — | US | disclosed |
| WO-2015157057-A1 | MACROCYCLES | LUMIPHORE, INC (US) | 2015-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210290787-A1 | MACROCYCLE CONJUGATES | FOLH1, KLK3, CD47 | P2RY6 4109/4885LMNA 3776/4885ALDH1A1 884/4885 |
| US-20200062757-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | P2RY6 2041/4885LMNA 3330/4885ALDH1A1 2862/4885 |
| US-11691997-B2 | Macrocycles | HCCS, ABCB7, AURKAIP1 | P2RY6 4014/4885LMNA 3079/4885ALDH1A1 1863/4885 |
| US-20240067650-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | P2RY6 2041/4885LMNA 3330/4885ALDH1A1 2862/4885 |
| US-20180194766-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | P2RY6 2041/4885LMNA 3330/4885ALDH1A1 2862/4885 |
| US-10273256-B2 | Macrocycles | HCCS, ABCB7, AURKAIP1 | P2RY6 4014/4885LMNA 3079/4885ALDH1A1 1863/4885 |
| US-20170183365-A1 | MACROCYCLES | HCCS, ABCB7, AURKAIP1 | P2RY6 4014/4885LMNA 3079/4885ALDH1A1 1863/4885 |
| US-10239878-B2 | Macrocyclic ligands with pendant chelating moieties and complexes thereof | TFRC, CLTC, SLC39A3 | P2RY6 2041/4885LMNA 3330/4885ALDH1A1 2862/4885 |
| US-20200405887-A1 | MACROCYCLIC LIGANDS WITH PENDANT CHELATING MOIETIES AND COMPLEXES THEREOF | TFRC, CLTC, SLC39A3 | P2RY6 2041/4885LMNA 3330/4885ALDH1A1 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.