Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.50 |
| ▸ | SNCA | P37840 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 2/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717617 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL1717907 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL1717912 | 0.92 | ALDH1A1 (0.50) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL3407627 | 0.89 | MAPT (0.65) | ALDH1A1CYP3A4ALOX15APPSNCA | |
| SCHEMBL3407633 | 0.89 | MAPT (0.65) | ALDH1A1CYP3A4ALOX15APPSNCA | |
| SCHEMBL1717884 | 0.87 | CYP26A1 (0.45) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL10067414 | 0.85 | MAPT (0.50) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL13252639 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL14519806 | 0.82 | RARG (0.45) | ALDH1A1CYP3A4ALOX15TSHRAPP | |
| SCHEMBL1718771 | 0.82 | ALDH1A1 (0.65) | ALDH1A1CYP3A4ALOX15APPSNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420610-B2 | Polyunsaturated compounds, method for preparing same and compositions containing the same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-04-16 | — | — | US | claimed |
| EP-1968993-B1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | FABRE PIERRE DERMO COSMETIQUE (FR) | 2012-01-11 | — | — | EP | claimed |
| US-20100168045-A1 | Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-07-01 | — | — | US | claimed |
| US-8420610-B2 | Polyunsaturated compounds, method for preparing same and compositions containing the same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2013-04-16 | — | — | US | disclosed |
| EP-1968993-B1 | NOVEL POLYUNSATURATED COMPOUNDS, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | FABRE PIERRE DERMO COSMETIQUE (FR) | 2012-01-11 | — | — | EP | disclosed |
| US-20100168045-A1 | Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168045-A1 | Novel Polyunsaturated Compounds, Method for Preparing Same and Compositions Containing the Same | CBR3, CBR1, DECR1 | ALDH1A1 396/4885CYP3A4 1393/4885ALOX15 24/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.