Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.59 |
| ▸ | NPY4R | P50391 | 13/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.53 |
| ▸ | NPY1R | P25929 | 8/20 | 0.53 |
| ▸ | NPY2R | P49146 | 5/20 | 0.53 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.52 |
| ▸ | TFPI | P10646 | 1/20 | 0.51 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17176397 | 0.90 | IL23R (0.55) | OPRM1OPRD1OPRK1NPY4RNPY5R | |
| SCHEMBL18331058 | 0.88 | OPRD1 (0.57) | OPRM1OPRD1OPRK1QRFPR | |
| SCHEMBL19953938 | 0.87 | TFPI (0.58) | OPRM1OPRD1OPRK1IL23RTFPI | |
| SCHEMBL30413829 | 0.86 | TFPI (0.60) | OPRM1OPRD1OPRK1IL23RTFPI | |
| SCHEMBL31257060 | 0.86 | NPY4R (0.58) | OPRM1OPRD1OPRK1NPY4RNPY5R | |
| SCHEMBL30414545 | 0.86 | TFPI (0.60) | OPRM1OPRD1OPRK1IL23RTFPI | |
| SCHEMBL30958545 | 0.85 | NPY4R (0.59) | OPRM1OPRD1OPRK1NPY4RNPY5R | |
| SCHEMBL29799960 | 0.85 | NPY4R (0.59) | NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL31504570 | 0.84 | TFPI (0.67) | OPRM1OPRD1OPRK1IL23RTFPI | |
| SCHEMBL29805232 | 0.84 | QRFPR (0.60) | OPRM1OPRD1OPRK1NPY4RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | Anglachem Inc. (CA) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | IDUA, GAA, MAN2B1 | OPRM1 4520/4885OPRD1 4575/4885OPRK1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.