Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.55 |
| ▸ | TFPI | P10646 | 1/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 5/20 | 0.50 |
| ▸ | NPY1R | P25929 | 4/20 | 0.50 |
| ▸ | NPY2R | P49146 | 4/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19953938 | 0.97 | TFPI (0.58) | IL23RTFPIOPRL1OPRM1OPRD1 | |
| SCHEMBL30413829 | 0.90 | TFPI (0.60) | IL23RTFPIOPRL1OPRM1OPRD1 | |
| SCHEMBL17176229 | 0.90 | OPRM1 (0.59) | IL23RTFPIOPRL1OPRM1OPRD1 | |
| SCHEMBL17176529 | 0.87 | OPRD1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL17176234 | 0.87 | OPRD1 (0.55) | OPRM1OPRD1OPRK1 | |
| SCHEMBL31504570 | 0.87 | TFPI (0.67) | IL23RTFPIOPRL1OPRM1OPRD1 | |
| SCHEMBL22807671 | 0.87 | TFPI (0.64) | IL23RTFPIOPRL1 | |
| SCHEMBL29372983 | 0.87 | TFPI (0.64) | IL23RTFPIOPRL1 | |
| SCHEMBL30412542 | 0.87 | TFPI (0.59) | IL23RTFPI | |
| SCHEMBL30810167 | 0.86 | NPY4R (0.59) | IL23RNPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | Anglachem Inc. (CA) | 2015-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | IDUA, GAA, MAN2B1 | IL23R 3331/4885TFPI 3118/4885OPRL1 4030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.