Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 19/20 | 0.42 |
| ▸ | TACR2 | P21452 | 8/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1717778 | 0.91 | PIK3CD (0.44) | TACR3TACR2OPRM1TRPV4 | |
| SCHEMBL1717879 | 0.89 | TACR3 (0.46) | TACR3TACR2OPRM1 | |
| SCHEMBL1718379 | 0.88 | TACR3 (0.36) | TACR3TACR2OPRM1TRPV4 | |
| SCHEMBL2676869 | 0.85 | TACR2 (0.40) | TACR3TACR2OPRM1TRPV4 | |
| SCHEMBL1717589 | 0.84 | TACR3 (0.45) | TACR3TACR2 | |
| SCHEMBL1718704 | 0.83 | TACR3 (0.43) | TACR3TACR2OPRM1 | |
| SCHEMBL1718684 | 0.83 | TACR3 (0.48) | TACR3TACR2OPRM1 | |
| SCHEMBL1717543 | 0.81 | HTR7 (0.46) | TACR3TACR2OPRM1 | |
| SCHEMBL1718231 | 0.80 | TACR3 (0.49) | TACR3TACR2OPRM1 | |
| SCHEMBL1717820 | 0.80 | TACR3 (0.51) | TACR3TACR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150534-B1 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2012-01-11 | — | — | EP | claimed |
| EP-2150534-B1 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS | LUNDBECK & CO AS H (DK) | 2012-01-11 | — | — | EP | disclosed |